[Is periodontal guided tissue regeneration a reproducible technic? A review of the literature].

: Guided tissue regeneration (GTR) has been developed as a surgical technique enabling the complete regeneration of the periodontal attachment apparatus. Among various periodontal tissues, the root, cementum and the alveolar bone, as well the Sharpey collagenic fibers linking the cementum to the bone, are of particular interest. As demonstrated in this literature review, we could globally conclude to date, that most of the publications confirm the biological and clinical potential of GTR, although in some publications, this opinion is not being shared. A number of factors influence the outcome of the regenerative therapy, some relating to the patient such as the smoking habits and the level of oral hygiene, others relating to the type of implanted biomaterial or the surgical technique. A better understanding of the periodontal healing mechanisms as well as the continuous research and progress in the field of biomaterials, chemical mediators and growth factors, are likely to further increase the predictibility of the periodontal regenerative treatments.