Simultaneous determination of 77 pesticides in oil plants and plant oil by high performance liquid chromatography-tandem mass spectrometry with QuEChERS

Objective To establish a method for the rapid determination of 77 kinds of pesticide residues in oil plants and plant oils by ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/ MS). Methods Samples were extracted by QuEChERS with acetonitrile, and purified with PSA+C18 cartridge. A gradient system of a mixture of 0.1% formic acid and acetonitrile with multi-reaction monitoring (MRM) were adopted for quantitative determination. Results Seventy-seven kinds of pesticide residues could be detected within 10 min, the correlation rate (r) was more than 0.99, and the average recoveries ranged from 60.2% to 99.8% with relative standard deviation (RSD) less than 8%. Conclusion This method is rapid, simple, sensitive and accurate, which is suitable for identification and quantification of multiple pesticide