A 1:1 cocrystal of fluconazole with salicylic acid

The interaction of the antifungal pharmaceutical agent fluconazole with salicylic acid in acetonitrile solution yields the 1:1 cocrystal 2-(2,4-difluoro­phenyl)-1,3-bis­(1H-1,2,4-tri­az­ol-1-yl)propan-2-ol–2-hy­droxy­benzoic acid (1/1), C13H12F2N6O·C7H6O3. The asymmetric unit consists of one molecule of fluconazole and one molecule of salicylic acid, both in their neutral forms. Both crystal agents form head-to-tail hydrogen-bonded dimers, which are further connected into hydrogen-bonded extended zigzag tapes propagating along the ac diagonal.