Antibacterial Activities of Some Antidiarrheal Herbal Concoctions Locally Prepared in Ilorin, Nigeria, on Fecal Isolates
2015
Antibacterial activity of herbal concoctions commonly used to treat diarrhea in Ilorin, Nigeria was determined against fecal isolates. Aqueous extracts of different combinations of the herbs used were prepared by soaking for eighteen days. Samples were taken daily for four days and weekly thereafter and used to challenge bacteria isolated from human feces. The efficacy of the herbal extracts was compared with a standard antibiotic, streptomycin. Most of the isolates were inhibited by the 48 hours herbal extracts. Inhibition zone ranged from 11.4 to 20.0 mm and 4.6 to 19.8 mm for the adult men and women extracts; and 9.6 to 32.0 mm for the children extract. The minimum inhibitory concentration ranged from 25 to 100%. Apart from Enterococcus feacalis and Staphylococcus aureus, susceptibility to the herbal extracts compared favorably with reference drug, streptomycin with percentage inhibition reaching 100, 120, 150 and 160 respectively for Proteus vulgaris, Salmonella enteritica, Escherichia coli, and Klebsiella sp. Aqueous extract of a combination of herbs used for treatment of diarrhea in Ilorin has antibacterial activity comparable with streptomycin and can therefore be recommended for use after determining its toxicity.
Keywords:
- Correction
- Cite
- Save
- Machine Reading By IdeaReader
0
References
0
Citations
NaN
KQI