COMPUTERIZED RESTING ECG ANALYSIS FOR THE DETECTION OF CORONARY ARTERY STENOSIS AFTER CORONARY REVASCULARIZATION IN COMPARISON WITH ANGIOGRAPHIC FINDINGS

Results: For patients with coronary stenosis the severity score was significantly higher than without (5.4 +/- 1.9 vs. 1.7 +/-2.1; p < 0.001, t-test). With a cut-off score of 4.0 3DMP correctly classified 192 patients (90.1% correct; sensitivity 93%, specificity 88.7%). Positive and negative predictive values were 80.5% and 96.2% respectively. The ROC area under the curve for the continuous severity score was 0.909 (95% CI: 0.867-0.952). The performance was not significantly different between patients with PCI and those with CABG (ROC AUC 0.907 [0.852-0.961] vs. 0.891 [0.803-0.978]). Conclusions: 3DMP provides a resting ECG methodology, which appears to be very sensitive and specific in the identification of patients with coronary stenosis after coronary revascularization. These results warrant additional studies with a direct comparison other noninvasive methods. Clinical Implications: 3DMP may be a valuable tool for diagnosing and screening patients who have undergone coronary revascularization for re-stenosis, de novo stenosis, or graft stenosis. As a resting ECG method 3DMP may be especially advantageous when stress test methods are contraindicated.