Prospective Advances in Beneficial Effects of Exercise on Human Health

: Physical inactivity increases the chance of many adverse health conditions. It has been well recognized that exercise exerts widespread beneficial effects in health promotion and disease prevention. However, there remain many unknowns in the understanding of the complex biology and performance behind diversity in response to exercise among populations and individuals. The exercise-afforded health benefits are not sufficiently researched, which to some extent holds back the translation of exercise biology to society and the widespread adoption of physical activity promotion. A comprehensive understanding of the physiology of exercise and pathogenic processes underpinning physical inactivity-associated disorders will facilitate the development of new preventative and therapeutic strategies to improve health and well-being at the whole-body level. In this chapter, we will discuss some important questions that remain to be addressed in the research of health-promoting benefits of exercise.