The xenogeneic transplantation of embryonic nerve tissue (the morphological and immunological aspects)

An analysis of the morphological and immunological aspects of xenotransplantation has shown that the xenotransplantation is a model for investigation of a wide range of problems of neurobiology: specific immune reactions in the brain and mechanisms of its immune privilege, conditions facilitating the take of transplants and mechanisms underlying autoimmune diseases of the CNS when the degenerative phase of the disease is accompanied by a cellular immune response. The use of xenotransplantations for studying potencies of the embryonic nerve tissues of man allowed to give grounds and to practically employ the method of treatment of parkinsonism. The first results of clinical use of the method obtained at the Institute of Experimental Medicine have shown its positive effects.