Probing nuclei with high-energy hadronic reactions

I review the subject of hadron-nucleus collisions at energies where peturbative theory is applicable. Reactions studied experimentally at the Fermilab Tevatron and CERN`s Super Proton Synchrotron include the Drell-Yan Process, direct photon production, quarkonium production, and open charm production. I conclude with an observation about a new era of proton-nucleus and nucleus-nucleus experiments which will be carried out at the hadron colliders, RHIC and LHC.