Results and observations on the research of circulating immunocomplexes in subjects with suspected autoimmune pathology

: The authors have investigated the level of circulating immune complexes (CIC) in 409 patients (some hospitalized) suffering from disease in which the presence of CIC had been suspected. The 10% (forty-one) was positive, and clinical manifestations related have shown, in the majority of patients, a close relation with diseases in which there was, or it was possible to presume, an immunological pathogenic mechanism. Besides the authors examine a case with close association between high level of CIC and leptospirosis.