Treatable traits as predictors of SABA overuse in the community

Background: A significant issue faced worldwide is the inappropriate use of asthma medications. There is a global problem with overuse of short-acting beta agonist (SABA) and underuse of inhaled corticosteroids (ICS). Treatable traits are modifiable elements that impact on symptoms, prognosis of airway disease and may attribute to patterns of medication use. The aim of this study was to identify clinical predictors of SABA overuse (SABA use ≥twice a week in the last 4 weeks) in the community. Method: Data from a real-world cross-sectional observational study capturing over-the-counter SABA purchasers in Australian community pharmacies was utilised. Correlational analysis and regression modelling were employed to determine potential predictors of SABA over users. Results: Of 412 participants aged ≥ 16 years, 70% were classified as SABA over users, 82% reported that they were instructed to use SABA ‘when required’, 37% were using ≥ 5 puffs of SABA a day. People who overused SABA inhalers were more likely to, think they have asthma, have cardiac disease, bothersome rhinitis symptoms, administer high maximum daily doses of SABA (in the previous 4 weeks), use SABA when no symptoms present, question the safety of their SABA, and report a lack of/insufficient information to effectively manage their condition. Conclusion: This research has uncovered a group of individuals who can completely self-manage their condition, without health care provider support or advice, despite having symptom-confounding comorbidities and being concerned about their SABA medication. By better understanding the factors that put these patients at risk of SABA overuse, we will be able to tailor interventions for these high-risk asthma patients.