One kind of a phosphonate prodrug derivatives and its application in medicine adenine

The present invention relates to phosphonate prodrugs and the use in medicine an adenine derivative. In particular, the present invention relates to a method as shown in formula (I) compound or an optical isomer, pharmaceutically acceptable salt, hydrate or solvate thereof, and their use in preparing medicine for treating viral infections, in particular B hepatitis (HBV), and a medicament in AIDS (HIV), wherein the same as defined in the definition of formula (I), each substituent group of specification.