Preparation method of completely fermented oxytetracycline calcium granules

The invention discloses a preparation method of completely fermented oxytetracycline calcium granules. By taking oxytetracycline fermentation liquor as an initiating raw material, the preparation method is used for preparing granules of the oxytetracycline calcium by virtue of steps of calcifying an oxytetracycline fermentation liquor as a raw material, acidizing, filtering, crushing, pelletizing, straightening, drying and sieving. The preparation method disclosed by the invention can be used for overcoming the defects that a conventional spray drying process is high in energy consumption and not environmentally-friendly, and the completely fermented oxytetracycline calcium granules obtained by adopting a conventional method have the defect of inconvenience in use. The oxytetracycline calcium granules prepared by adopting the preparation method disclosed by the invention is uniform, compact, beautiful, good in mobility, unlikely to crush, convenient to use and capable of meeting the needs of a client very well.