N-ARYL-2,3-DIAROYL-8,10-DIMETHYLPYRIDO[2',3',3,4]PYRAZOLO[1,5-α]PYRIMIDINE-4-CARBOXAMIDE AND METHOD FOR PREPARING THEM

FIELD: medicine, pharmaceutics. SUBSTANCE: invention refers to new N-aryl-2,3-diaroyl-8,10-dimethylpyrido[2',3':3,4]pyrazolo[1,5-α]pyrimidine-4-carboxamides of formula I possessing analgesic activity, and to a method for preparing them. In formula I Ar 1 =Ph, C 6 H 4 Me-4, C 6 H 4 OMe-4; Ar 2 -Ph, C 6 H 4 Me-4, C 6 H 3 (Me) 2 -2,5. The method for preparing said compounds consists in a reaction of 1-aryl-4,5-diaroyl-1H-pyrrol-2,3-diones with 3-amino-4,6-dimethyl-2H-pyrazolo[3,4-6]pyridine at temperature 108-110°C in an absolute toluene medium. EFFECT: there are prepared the compounds possessing analgesic activity. 4 cl, 1 dwg, 1 tbl, 3 ex