Synthesis and Anti-Hcv Activity of N 9, 5′-Cyclo-3-(β-D-Ribofuranosyl)-8-Azapurin-2-One Derivatives
2005
A number of 1- or 6-substituted N 9 ,5′-cyclo-3-(β-D-ribofuranosyl)-8-azapurin-2-one derivatives were synthesized in multi-step reactions. Their anti-hepatitis C virus activities were evaluated and some structure–activity relationship is discussed.
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