Досвід двадцятирічного застосування ОФЕКТ/КТ в ядерній медицині

The review discusses the results of twenty years of experience using single-photon emission computed tomography/computed tomography (SPECT/CT). Hybrid imaging, including the use of SPECT in combination with CT, translates molecular and metabolic information directly onto the clinical effect of a wide range of diseases. At the same time, SPECT/CT further improve the diagnostic accuracy, specificity and positive prognostic value of nuclear medicine research. It was considered expedient to carry out a review of modern SPECT/CT applications, not only from the perspective of a diagnostic tool, but to integrate this modality into the clinical process. To this end, complex technological issues are being resolved for attracting new radiopharmaceuticals to use SPECT/ CT, improving the quality of protocols for obtaining diagnostic images, quantifying them, as well as compiling protocols for dosimetry and radiation exposure that are beyond the scope of the current review.