Improving Prostate Brachytherapy Quality Assurance with MRI-based Sector Analysis in a Phase II Prospective Trial

Purpose/Objectives: Sector analysis is a clinical tool that can be used in the post-implant quality assurance process for prostate brachytherapy by calculating the dose delivered to different sectors within the prostate. Each sector can be correlated to biopsy results for individual patients. However, sector analysis has not been translated to clinical practice, in part due to poor anatomic visualization of the prostate base and apex on post-implant CT scans. The purpose of this study is to evaluate MRI-based sector analysis as a method to improve the post-implant quality assurance process of brachytherapy.