P54A case of Gollop Wolfgang complex: prenatal diagnosis and pregnancy termination

Objective To report a prenatal diagnosis of Gollop Wolfgang complex. Case history This is a pregnant women of 29 years of age, G:2 P:1 Ab:0 with 23 weeks of gestation, has not any history of drug use nor infection during pregnancy. Her husband 29 years of age, has not any family history of anomaly nor medical illness of skeletal deformity as his wife. Ultrasound examination of this pregnancy at 16 weeks gestation showed pes equinovarus deformity and an absence of distal bone of right extremity. The family was informed about the problem. At the meantime ethical permission was obtained for termination of this pregnancy. At 23th weeks, after having family's consent for termination of pregnancy, careful ultrasound examination of the fetus was carried out; double distal femoral epiphysis with ipsilateral deficiency of distal bone (tibia or fibula) and pes equinovarus of the right lower extremity were diagnosed. After cervical priming and induction of labor, female fetus with 1-1-1 Apgar scoring at 1st, 5th and 10th minute was born. There was also hypoplastic right knee joint with bony prominence and flexion contracture at the right leg. X-rays of whole body were taken. There was also some other deformities and absence of some small bones. Conclusion This is the first case of prenatal diagnosis of Wolfgang Complex. We showed the importance of a careful ultrasound examination of fetus in the first and second trimesters for the diagnosis of fetal malformation.