Carriage and drug susceptibility of Streptococcus pneumoniae among healthy population in Shenzhen

Objective To learn about the carriage and drug susceptibility of Streptococcus pneumoniae(Sp) among the healthy population in Shenzhen.Methods A total of 521 throat swabs were taken from the healthy people in different age groups in Shenzhen,and Sp was isolated from the throat swabs.The drug susceptibility test was conducted with VITEK 2-Compact.Results Forty strains of Sp were isolated,the overall carriage rate was 7.7%.All 40 strains were sensitive to gatifloxacin,moxifloxacin,linezolid,vancomycin and rifampicin;and were highly resistant to benzylpenicillin,trimethoprim,erythromycin and tetracycline.Conclusion The oral pharyngeal carriage rate of Sp was 7.7% among the healthy population in Shenzhen.The Sp strains showed high resistance to macrolides,sulfanilamide and benzylpenicillin,which should be used cautiously in prophylaxis and therapy.