Analysis and management of 59 AIDS occupational exposure cases.

Objective To get the message of current situation of AIDS occupational exposure and discuss factors influencing the post exposure prophylaxis. Method 59 AIDS occupational exposure cases occuring in the eighth people's hospital of Guangzhou from 2001 to 2008 were analysed. Result 41 cases had pricking wound, about 69.5% of the total,17 cases (28.8%)were exposed from skin or mucous membrane contact and only 1 case (1.7%) had scratching. Overall,23 cases (39.0%) were grade 1 exposure, 35 cases (59.3%) were grade 2 exposure,and 1 cases (1.7%)was grade 3 exposure. 2 case of the exposure source had low viral load (3.4%),41 cases of the exposure source had high viral load (69.5%),and 16 cases had undefined viral load (27.1%). In the 59 cases, 26 cases (44.1%) used the medicine for the prevention treatment, of which 23 cases used the basic chemoprophylaxis,and 3 cases (5.1%)used the strengthened chemoprophylaxis. The follow-up observation was made after 6 months and the results were all negative. Conclusion Medical staff should keep protective measures strictly in the process of diagnosing and treating AIDS patients and HIV carriers. The timely using of chemoprophylaxis could block infection after occupational exposure effectively.