Interaction of Quinolones Carrying New R1 Group with Mycobacterium leprae DNA Gyrase.

Jong-Hoon Park,Tomoyuki Yamaguchi,Yuki Ouchi,Kentaro Koide,Ruttana Pachanon,Joseph Yamweka Chizimu,Shigetarou Mori,Hyun Kim,Tetsu Mukai,Chie Nakajima,Yasuhiko Suzuki

Interaction of Quinolones Carrying New R1 Group with Mycobacterium leprae DNA Gyrase.

2021

Jong-Hoon Park
Tomoyuki Yamaguchi
Yuki Ouchi
Kentaro Koide
Ruttana Pachanon
Joseph Yamweka Chizimu
Shigetarou Mori
Hyun Kim
Tetsu Mukai
Chie Nakajima
Yasuhiko Suzuki

Background: Leprosy is a chronic infectious disease caused by Mycobacterium leprae and the treatment of choice is ofloxacin (OFX). Specific amino acid substitutions in DNA gyrase of M. leprae have ...

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