A new 5H-purin-6-amine from the leaves of Sedum sarmentosum

Phytochemical constituents were isolated from Sedum sarmentosum leaves using open column chromatography and medium-pressure liquid chromatography. Their structures were identified as 2,4-pyrimidinedione (1), N-methylhydroxylamine (2), 5H-purin-6-amine (3), uridine (4), l-tyrosine (5), and l-prolyl-l-tyrosine (6) using mass spectrometry and 1H- and 13C-nuclear magnetic resonance spectroscopic analysis. Among them, compound 3 (5H-purin-6-amine) was isolated for the first time from a natural source.