Reticuloendothelial activity in rats with Yoshida sarcoma

Abstract Double-tracer method using 131 I -labelled HSA-microspheres and Na 125 I was applied for determining the proteolytic activity of reticuloendotheliai system in ascitic and solid Yoshida sarcoma-bearing rats. The mean permanence time of labelied microspheres was shortened in rats with ascitic form (0.78 days) as well as in animals with solid form (1.66 days) as compared with that in intact animals (4.53 days) . The reproducibility of the method was confirmed.