Synthesis and anti-HIV Activity of Some New Aminoadamantane Heterocycles.
1997
A new class of aminoadamantane heterocycles has been synthesized and examined for anti-HIV activity. Three compounds proved to be active against the replication of HIV-1 in MT-4 cells with an EC50 ranging from 3.6 to 75.2 μM. No activity was noted with any of the compounds against HIV-2.
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