Effect of Structural Rearrangements on Chiasma Frequency in Mouse Oocytes

A study of total chiasma frequencies in the diplotene oocytes of mice heterozygous for Robertsonian translocations, X-autosomal translocations, paracentric inversions as well as the XX progeny of XO mothers revealed a decrease in all but one genotype. These data present the first analysis of potential interchromosomal effects on crossing over in mouse oogenesis.