Bone and Joint Infections Caused by : Report of Two Cases and Literature Review haemophilus parainfluenzae : Report of Two Cases and Literature Review

Abstract Haemophilus parainfluenzae has been implicated in septic arthritis and osteomyelitis, but its role remains uncertain in view of its assumed low pathogenicity and of its being a fastidious organism. Reported in this study are 2 cases of bone and joint infections caused by H. parainfluenzae (vertebral osteomyelitis with epidural and psoas abscesses, and sacroiliitis with osteomyelitis), followed by a review of the corresponding English-language literature. Ten previously reported cases were discussed together with our 2 cases. Up to 75% of patients were found to have a predisposing factor before infection. The hematogenous spread was the most likely route of infection. Eleven of these 12 patients were cured, and one was improved clinically by antibiotic therapy alone or in conjunction with surgery.