Abstract 11795: Identification of Celastramycin as a Novel Therapeutic Agent for Pulmonary Arterial Hypertension -High-throughput Screening of 5,562 Compounds-

Ryo Kurosawa,Kimio Satoh,Nobuhiro Kikuchi,Taijyu Satoh,Junichi Omura,Masamichi Nogi,Shinichiro Sunamura,Mohammad Abdul Hai Siddique,M. Elias Al-Mamun,Nobuhiro Yaoita,Toru Shimizu,Hiroaki Shimokawa

Abstract 11795: Identification of Celastramycin as a Novel Therapeutic Agent for Pulmonary Arterial Hypertension -High-throughput Screening of 5,562 Compounds-

2019

Ryo Kurosawa
Kimio Satoh
Nobuhiro Kikuchi
Taijyu Satoh
Junichi Omura
Masamichi Nogi
Shinichiro Sunamura
Mohammad Abdul Hai Siddique
M. Elias Al-Mamun
Nobuhiro Yaoita
Toru Shimizu
Hiroaki Shimokawa

Introduction: Pulmonary arterial hypertension (PAH) is characterized by enhanced proliferation of pulmonary artery smooth muscle cells (PASMCs) accompanying increased production of inflammatory fac...

Keywords:

Pulmonary artery
Inflammation
Pulmonary hypertension
Internal medicine
Cardiology
smooth muscle
Medicine
High-throughput screening

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