A multidrug LC–MS/MS method for the determination of five immunosuppressants in oral fluid

Lucía Paniagua-González,Elena Lendoiro,Esteban Otero-Antón,Esther Molina-Pérez,Evaristo Varo-Pérez,Manuel López-Rivadulla,Angelines Cruz,Ana de-Castro-Ríos

A multidrug LC–MS/MS method for the determination of five immunosuppressants in oral fluid

2019

Lucía Paniagua-González
Elena Lendoiro
Esteban Otero-Antón
Esther Molina-Pérez
Evaristo Varo-Pérez
Manuel López-Rivadulla
Angelines Cruz
Ana de-Castro-Ríos

Aim: This study aimed: to develop and validate an LC–MS/MS method for mycophenolic acid, tacrolimus, sirolimus, everolimus and cyclosporin A in oral fluid (OF), as an essential tool to study the us...

Keywords:

Mycophenolic acid
Therapeutic drug monitoring
Sirolimus
Everolimus
Tacrolimus
Chromatography
Liquid chromatography–mass spectrometry
Chemistry
lc ms ms
oral fluid
cyclosporin a

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