A small molecule fibrokinase inhibitor in a model of fibropolycystic hepatorenal disease

Prani Paka,Brian Huang,Bin Duan,Jingsong Li,Ping Zhou,Latha Paka,Michael A. Yamin,Scott L. Friedman,Itzhak D. Goldberg,Prakash Narayan

A small molecule fibrokinase inhibitor in a model of fibropolycystic hepatorenal disease

2018

Prani Paka
Brian Huang
Bin Duan
Jingsong Li
Ping Zhou
Latha Paka
Michael A. Yamin
Scott L. Friedman
Itzhak D. Goldberg
Prakash Narayan

AIM To evaluate the novel platelet-derived growth factor receptor and vascular endothelial growth factor receptor dual kinase inhibitor ANG3070 in a polycystic kidney disease-congenital hepatic fibrosis model.

Keywords:

Small molecule
Biochemistry
Biology
Renal function
Albuminuria
Congenital hepatic fibrosis
Urology
Urinary system
Creatinine
hepatic fibrosis
Kidney
Medicine
Cystatin C

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