Predictors of antiproliferative effect of lanreotide autogel in advanced gastroenteropancreatic neuroendocrine neoplasms

Faidon-Marios Laskaratos,Eleni Armeni,Heer Shah,Maria Megapanou,Dimitrios Papantoniou,Aimee R Hayes,Shaunak Navalkissoor,Gopinath Gnanasegaran,Conrad von Stempel,Edward Phillips,Myles Furnace,Lukasz Kamieniarz,Margarita Kousteni,Tu Vinh Luong,Jennifer Watkins,Dalvinder Mandair,Martyn Caplin,Christos Toumpanakis

Predictors of antiproliferative effect of lanreotide autogel in advanced gastroenteropancreatic neuroendocrine neoplasms

2019

Faidon-Marios Laskaratos
Eleni Armeni
Heer Shah
Maria Megapanou
Dimitrios Papantoniou
Aimee R Hayes
Shaunak Navalkissoor
Gopinath Gnanasegaran
Conrad von Stempel
Edward Phillips
Myles Furnace
Lukasz Kamieniarz
Margarita Kousteni
Tu Vinh Luong
Jennifer Watkins
Dalvinder Mandair
Martyn Caplin
Christos Toumpanakis

Purpose The antiproliferative properties of lanreotide autogel (LAN) in gastroenteropancreatic neuroendocrine neoplasms (GEP NENs) were demonstrated in the CLARINET study. However, there is limited literature regarding factors that affect progression-free survival (PFS) in patients with GEP NENs treated with LAN.

Keywords:

Neuroendocrine neoplasm
Lanreotide Autogel
Biology
Oncology
Somatostatin Analogue
Endocrinology
Internal medicine
Metastatic liver disease
Diabetes mellitus
Positron emission tomography
Gastroenterology
Multivariate analysis
Progressive disease
Cohort
Rectum
Univariate analysis

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