Gene expression profiling of lymph node positive-negative metastasis of primary breast cancer in Saudi Arabian patients

Background Breast cancer is the most frequent and most deadly cancer in females and incidence rates are increasing at an alarming rate in Saudi Arabia [1]. Studies have shown the potential of gene expression profiling in discovering biomarkers and molecular genetic signatures for breast cancer [2-4]. However, such discoveries and association of expression profiling with different type of Saudi Arabian breast cancer patients are largely unexplored.