The Reversible Change in the Redox State of Type I Cu in Myrothecium verrucaria Bilirubin Oxidase Depending on pH

The redox state of type I Cu in Myrothecium verrucaria bilirubin oxidase (BO), a multicopper oxidase utilized in the clinical investigation of liver, is an equilibrium state of the oxidized and reduced forms, reflected in the reversible absorption and electron paramagnetic resonance (EPR) spectral changes depending on pH.