Design of a virtual sensor test platform for ICU patient glucose-insulin system using the HIL technique

The traditional simulation In Silico (computational simulation) does not allow to recreate realistic environments. Tools like hardware-in-the-loop (HIL) allow the real-time simulation of the response of a system to disturbances. These tools come in handy for the study of the variations in glucose regulation for a patient in the Intensive Care Unit, such as hyperglycemia or hypoglycemia. In this investigation, a methodology was developed using HIL simulation technique to create a test platform for virtual sensors for the system patients' glucose – insulin in UCI. Also, state estimation techniques were employed, requiring the use of a communication structure to submit the system to real-time disturbances. Moreover, the work involved the development of an interface for the manipulation of the principal characteristics and parameters of both the model and the virtual sensors.