Assessment of Cancerogenic Health Risk of as, Cd, Pb and Ni from Tobacco Smoke

The aim of this study was to determine the cancerogenic risk to human health of As, Cd, Pb, and Ni intake via cigarette tobacco smoke, made primarily from indigenous Herzegovina tobacco varieties. Since such research has never been done on these Herzegovina varieties VH, VH32, and Ravnjak, they radically compared the possibilities next to them, examining the cultivar Virginia and Berley, also produced in BiH. Samples were taken from 16 localities, namely, all localities in BiH today. Samples were used per insertion, from medium insertions, such as the highest quality, handmade cigarettes that were later dropped on smokers, and the smoke condensate tested for Cd, Pb, As, and Ni content. A tobacco smoke cancerogenic risk assessment was made after setting up the CSF by the US EPA, assuming that 1 pack of cigarettes is smoked daily. CDI - chronic daily dose for 4 heavy metals and ILCR for each type of tobacco was determined. CDI Calculated risk had cancer over the life span of As, Cd, Pb, and Ni ranging from 1.17E−4 for Virginia to 1.48E−4 for Ravnjak, which did not reach the common benchmark of 10−6–10−4 is used by the US EPA to protect public health.