Nickel-Catalyzed Asymmetric Addition of Aromatic Halides to Ketones: Highly Enantioselective Synthesis of Chiral 2,3-Dihydrobenzofurans Containing a Tertiary Alcohol.

Ying Li,Wendian Li,Jiangyan Tian,Guozheng Huang,Hui Lv

Nickel-Catalyzed Asymmetric Addition of Aromatic Halides to Ketones: Highly Enantioselective Synthesis of Chiral 2,3-Dihydrobenzofurans Containing a Tertiary Alcohol.

2020

Ying Li
Wendian Li
Jiangyan Tian
Guozheng Huang
Hui Lv

A highly enantioselective and straightforward synthetic procedure to chiral 3-hydroxy-2,3-dihydrobenzofurans has been developed by nickel/bisoxazoline-catalyzed intramolecular asymmetric addition o...

Keywords:

Halide
Chemistry
Catalysis
Alcohol
Chirality (chemistry)
Organic chemistry
Nickel
Ketone
Intramolecular force
Enantioselective synthesis

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