Relationship between Vitamin D Levels and Depressive Symptoms in Renal Transplant Recipients

Objective:Vitamin D deficiency might influence the development of depression; however, the association between vitamin D and depression in renal transplant recipients has not been evaluated. We aimed to test if there is a relation between 25-hydroxy (OH) vitamin D levels and depressive symptoms in patients with kidney transplantation.Methods:This was a cross-sectional and descriptive study. A total of 117 renal transplant recipients (44 female, 73 male; mean age, 39.0 ± 11.7 years) were included in the study. Patients were stratified to two groups according to the cut-off point (7) of depression subscale (D) of Hospital Anxiety Depression Scale (HADS), with or without depression risk. Blood biochemistry, glomerular filtration rate (GFR), and 25-OH vitamin D levels were determined.Results:Depression scores were higher than cut-off point in 33.3% (n = 39) of patients. The mean 25-OH vitamin D level was 19.6 ± 12.0 µg/L. In the group with depression risk, 25-OH vitamin D levels were significantly lower than ...