Synthesis of 3-substituted carboxylate/carboxamide flavone derivatives from 4-hydroxycoumarin, β-nitrostyrene and alcohol/amine using multicomponent reaction
2016
Abstract A wide range of 3-substituted carboxylate/carboxamide flavone derivatives were synthesized from 4-hydroxycoumarin, β-nitrostyrene and alcohol/amine using multicomponent reaction in the presence of N , N -dimethyl-4-aminopyridine (DMAP). Good yield, short reaction time, atom economy, cost effectiveness, and use of non-toxic organo-catalyst are some of the remarkable advantages of the present protocol.
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