Genetic study of KIR and HLA ligands in 235 individuals from Northeastern Thailand

Abstract The diversity of 17 KIR and HLA ligands ( HLA-C1 , C2 , Bw4 , A11 ) were investigated in two hundred and thirty-five unrelated healthy donors in Northeastern Thais (NETs) by the polymerase chain reaction with sequence-specific primer (PCR-SSP) method. The Hardy-Weinberg Equilibrium (HWE) was used to verify genotyping method for dimorphic KIR and HLA . They were in HWE ( p  > 0.05). KIR and HLA ligands frequencies, genotypes, haplotypes and linkage disequilibrium (LD) were presented. The genetic data are available in allele Frequencies Net Database.