Probiotic potential of lactobacillus strains in human infections

Probiotics means “for life”. Probiotics are naturally occurring beneficial organisms that aid in digestion and inhibit disease-causing bacteria in the intestine. Due to the beneficial impact of microorganism used as Probiotics; during the last decades progressive attention has been focused on biological and molecular characterization and improvement of such microbes during the last decades. Probiotics in the strictest sense, refers to lactic acid producing bacteria Most data accumulated so far have related that lactic acid bacteria are major organisms, which that when given orally will pass through the strong acid of the stomach and the low surface tension of bile and colonize in the intestine, which is their normal habitat. Lactic acid bacteria mainly include Lactobacilli and Bifidobacteria. Various studies have indicated that lactobacillus species may have a positive influence on the intestinal flora of human, alleviate lactose intolerance, have hypocholesterolemic effect, stimulate immunity and have anti-colon cancer effects, Crohn’s disease and candidiasis infections. Interest in the field of probiotics has bloomed in recent years and considering the above impressive list of potential health-promoting benefits, it is not surprising that there continues to be considerable interest in the use of probiotics as biotherapeutic tool to improve the diseased conditions of humans although much remains to be elucidated.