Preparation and crystallization conditions screening method of crystal nuclei

The present invention is a crystal of a protein or an organic substance, to a method of efficiently easily produced with high quality. The solution of protein and organics were prepared and the low degree of supersaturation by slowly cooling it. This supersaturated solution is irradiated with femtosecond laser 10. The focus of the laser, the crystal nuclei are generated happening localized explosions. Based on the crystal nucleus, be grown crystals over time, high-quality crystals are obtained. The femtosecond laser, wavelength 800 nm, time width 120 fs, frequency 1 kHz, titanium sapphire laser output 400mW can be used.