MiR-9 promotes tumorigenesis and angiogenesis and is activated by MYC and OCT4 in human glioma

Background Glioma, characterized by its undesirable prognosis and poor survival rate, is a serious threat to human health and lives. MicroRNA-9 (miR-9) is implicated in the regulation of multiple tumors, while the mechanisms underlying its aberrant expression and functional alterations in human glioma are still controversial.