Fructus Podophylli extract and application thereof

The invention relates to a Fructus Podophylli extract and an application of the extract and active ingredients in the extract to the preparation of a medicament for treating breast cancer. The Fructus Podophylli extract contains podophyllotoxin, deoxypodophyllotoxin, 4'-demethyldeoxypodophyllotoxin, 8-isopentenylkaempferol and a new compound of 8,2'-diprenylquercetin3-methyl ether. The experimentof the inhibited effect of the Fructus Podophylli extract and compounds on human breast cancer cells shows that the Fructus Podophylli extract and the compounds have the effect of inhibiting breast cancer cells. Besides, the compatibility use of podophyllotoxin lignanoids and isopentenyl flavone ingredients has the cooperative function and can remarkably improve the effect of inhibiting the breast cancer cells.