Simple method for preparing PLGA microspheres with uniform particle size

The invention provides an improved stirring emulsification method for preparing PLGA microspheres with the uniform particle size. The particle size distribution of the microspheres prepared through the method is narrower, and the PLGA microspheres with the uniform particle size can be obtained through simple centrifugation enriching at a higher yield. The preparation method comprises the steps that PLGA is dissolved in dichloromethane to serve as an oil phase, a PVA solution serves as a water phase, the oil phase is dispersed into the water phase according to a certain ratio, a plurality of glass balls with the diameter of 2-8 mm are added to assist in emulsification, and then stirring emulsification is performed with a magnetic stirrer; the PLGA microspheres with the uniform particle size are obtained through organic solvent volatilizing, washing and differential centrifugation enriching.