Pirmenol hydrochloride (CI-845) : antiarrhythmic profile in coronary artery ligated conscious dogs

The antiarrhythmic profile of CI-845 (pirmenol hydrochloride) was assessed in conscious, coronary artery ligated dogs. In single-dose studies in these arrhythmic dogs, CI-845 administered by the intravenous, intramuscular, and oral routes was highly effective in restoring normal sinus rhythm. A 2.5