Gene-based Association Testing of Dichotomous Traits with Generalized Linear Mixed Models Using Extended Pedigrees: Applications to Age-related Macular Degeneration

Yingda Jiang,Chi Yang Chiu,Qi Yan,Wei Chen,Michael B. Gorin,Yvette P. Conley,M'Hamed Lajmi Lakhal-Chaieb,Richard J. Cook,Christopher I. Amos,Alexander F. Wilson,Joan E. Bailey-Wilson,Francis J. McMahon,Ana I. Vazquez,Ao Yuan,Xiaogang Zhong,Momiao Xiong,Daniel E. Weeks,Ruzong Fan

Gene-based Association Testing of Dichotomous Traits with Generalized Linear Mixed Models Using Extended Pedigrees: Applications to Age-related Macular Degeneration

2020

Yingda Jiang
Chi Yang Chiu
Qi Yan
Wei Chen
Michael B. Gorin
Yvette P. Conley
M'Hamed Lajmi Lakhal-Chaieb
Richard J. Cook
Christopher I. Amos
Alexander F. Wilson
Joan E. Bailey-Wilson
Francis J. McMahon
Ana I. Vazquez
Ao Yuan
Xiaogang Zhong
Momiao Xiong
Daniel E. Weeks
Ruzong Fan

Genetics plays a role in age-related macular degeneration (AMD), a common cause of blindness in the elderly. There is a need for powerful methods for carrying out region-based association tests bet...

Keywords:

age related
Genetics
Statistics
Macular degeneration
Blindness
Association tests
Pedigree chart
Mathematics
Gene
Generalized linear mixed model

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations