Ultrastructure of Acute Inflammation

The gross morphological aspects of acute inflammation were known by the ancient world (Majno, 1975). One had, however, to wait for investigations of Julius Cohnheim (1867, 1873, 1889) and Elie Metschnikoff (1893, 1907) to get some insight, at the microscopic level, into the histologic changes observed during the first phase of inflammation.