A PK/PD Analysis of Circulating Biomarkers and Their Relationship to Tumor Response in Atezolizumab‐Treated non‐small Cell Lung Cancer Patients

Ida Netterberg,Chi‐Chung Li,Luciana Molinero,Nageshwar Budha,Siddharth Sukumaran,Mark Stroh,E. Niclas Jonsson,Lena E. Friberg

A PK/PD Analysis of Circulating Biomarkers and Their Relationship to Tumor Response in Atezolizumab‐Treated non‐small Cell Lung Cancer Patients

2019

Ida Netterberg
Chi‐Chung Li
Luciana Molinero
Nageshwar Budha
Siddharth Sukumaran
Mark Stroh
E. Niclas Jonsson
Lena E. Friberg

To assess circulating biomarkers as predictors of antitumor response to atezolizumab (anti-programmed death-ligand 1 (PD-L1), Tecentriq) serum pharmacokinetic (PK) and 95 plasma biomarkers were ana ...

Keywords:

Anesthesia
PK/PD models
Lung cancer
Cancer research
Atezolizumab
Biomarker (medicine)
Medicine
Diabetes mellitus
circulating biomarkers
tumor response
non small cell
Pharmacokinetics

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