Inhibition of γ-secretase in adipocytes leads to altered IL-6 secretion and adipose inflammation

David P. Sparling,Nile Mccullough,Utpal B. Pajvani,Mary Beth Humphrey

Inhibition of γ-secretase in adipocytes leads to altered IL-6 secretion and adipose inflammation

2020

David P. Sparling
Nile Mccullough
Utpal B. Pajvani
Mary Beth Humphrey

Adipocyte-mediated inflammatory signalling has been proposed to alter adipose physiology in obesity and Type 2 diabetes mellitus. Novel targets for alteration of inflammatory signalling are needed ...

Keywords:

Inflammation
Adipocyte
Chemistry
γ secretase
Adipose tissue
Endocrinology
Internal medicine
Gamma secretase
Type 2 Diabetes Mellitus
Interleukin 6
Secretion

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