Lactone-driven ester-to-amide derivatization for sialic acid linkage-specific alkylamidation (LEAD-SALSA).

Jun-ichi Furukawa,Hisatoshi Hanamatsu,Takashi Nishikaze,Hiroshi Manya,Nobuaki Miura,Hirokazu Yagi,Ikuko Yokota,Keiko Akasaka-Manya,Tamao Endo,Motoi Kanagawa,Norimasa Iwasaki,Koichi Tanaka

Lactone-driven ester-to-amide derivatization for sialic acid linkage-specific alkylamidation (LEAD-SALSA).

2020

Jun-ichi Furukawa
Hisatoshi Hanamatsu
Takashi Nishikaze
Hiroshi Manya
Nobuaki Miura
Hirokazu Yagi
Ikuko Yokota
Keiko Akasaka-Manya
Tamao Endo
Motoi Kanagawa
Norimasa Iwasaki
Koichi Tanaka

Sialic acid attached to nonreducing ends of glycan chains via different linkages is associated with specific interactions and physiological events. Linkage-specific derivatization of sialic acid is...

Keywords:

Chemistry
Amide
Stereochemistry
Derivatization
Lactone
Glycoconjugate
Amine gas treating
Galactose
Sialic acid
Glycan

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