Excretion, Metabolism and Cytochrome P450 Inhibition of Methyl 3,4-Dihydroxybenzoate (MDHB): A Potential Candidate to Treat Neurodegenerative Diseases

Jia-Hui Wang,Ke-Qi Chen,Jun-Xing Jiang,Huan Yong Li,Jun-Ping Pan,Ji-Yan Su,Lin Wang,Yang Hu,Xiang-Nan Mi,Yi-Rong Xin,Qin Gao,Xiang-long Zhao,Fei Xiao,Huan-min Luo

Excretion, Metabolism and Cytochrome P450 Inhibition of Methyl 3,4-Dihydroxybenzoate (MDHB): A Potential Candidate to Treat Neurodegenerative Diseases

2019

Jia-Hui Wang
Ke-Qi Chen
Jun-Xing Jiang
Huan Yong Li
Jun-Ping Pan
Ji-Yan Su
Lin Wang
Yang Hu
Xiang-Nan Mi
Yi-Rong Xin
Qin Gao
Xiang-long Zhao
Fei Xiao
Huan-min Luo

Background and Objectives Methyl 3,4-dihydroxybenzoate (MDHB) has the potential to prevent neurodegenerative diseases (NDDs). The present work investigated its excretion, metabolism, and cytochrome P450-based drug–drug interactions (DDIs).

Keywords:

Cytochrome P450
Biochemistry
Excretion
Chemistry
Metabolism
potential candidate

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