Transgenic rabbits expressing human lipoprotein (a) in function

(57) Abstract: The binding to lipoprotein (a) the encoding apolipoprotein (a) polypeptide and apolipoprotein B polypeptides can be produced sequences, transgenic rabbits with the genomic DNA, creation of such Rabbits method, and then associated with Lp (a) expression, induced by Lp (a) expression, and / or use of the rabbit for identifying compounds effective in the treatment of exacerbated human diseases.